1H-Indole, 7-bromo-3-iodo-
1H-Indole, 7-bromo-3-iodo-
CAS: 793727-95-4
Molecular Formula: C8H5BrIN
1H-Indole, 7-bromo-3-iodo- - Names and Identifiers
| Name | 1H-Indole, 7-bromo-3-iodo- |
| Synonyms | 3-iodo-7-bromoindole 7-Bromo-3-iodo-1H-indole 1H-Indole,7-broMo-3-iodo- 1H-Indole, 7-bromo-3-iodo- tert-butyl 7-broMo-3-iodo-1H-indole-1-carboxylate |
| CAS | 793727-95-4 |
1H-Indole, 7-bromo-3-iodo- - Physico-chemical Properties
| Molecular Formula | C8H5BrIN |
| Molar Mass | 321.94 |
| Boling Point |
1H-Indole, 7-bromo-3-iodo- - Introduction
1H-Indole, 7-bromo-3-iodo- (1H-Indole, 7-bromo-3-iodo-) is an organic compound with the chemical formula C8H4BrIN. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: white or light yellow crystalline solid.
2. Melting point: about 90-92°C.
3. Solubility: Soluble in organic solvents such as polyethylene glycol and dimethyl sulfoxide, slightly soluble in ethanol and sodium hydroxide solution.
Use:
1H-Indole, 7-bromo-3-iodo-is an important intermediate in organic synthesis, which has certain application value in the fields of medicine and agriculture. It can be used to synthesize indole derivatives, such as indole carboxylate derivatives, which have antitumor and antiviral activities in the pharmaceutical field. In addition, 1H-Indole, 7-bromo-3-iodo-can also be used as pesticide intermediates for the synthesis of compounds having insecticidal activity.
Preparation Method:
The method of preparing 1H-Indole, 7-bromo-3-iodo-is generally obtained by taking indole as a starting material and transforming it through a series of chemical reactions. A common synthetic method is to brominate indole with bromine chloride and then react the resulting product with hydroiodic acid to give 1H-Indole, 7-bromo-3-iodo-.
Safety Information:
Due to the toxicity and irritation of 1H-Indole, 7-bromo-3-iodo-during preparation and use, corresponding safety measures should be taken. Personal protective equipment such as protective gloves, goggles and protective clothing are required to be worn during operation to avoid contact with skin and inhalation. At the same time, it also needs to be stored in a dry and ventilated place, away from fire and oxidant, and has potential harm to the environment, and requires proper treatment and relevant regulatory measures for waste disposal. In the process of use and handling, it is necessary to comply with the relevant regulations for the transportation, storage and handling of dangerous goods.
Nature:
1. Appearance: white or light yellow crystalline solid.
2. Melting point: about 90-92°C.
3. Solubility: Soluble in organic solvents such as polyethylene glycol and dimethyl sulfoxide, slightly soluble in ethanol and sodium hydroxide solution.
Use:
1H-Indole, 7-bromo-3-iodo-is an important intermediate in organic synthesis, which has certain application value in the fields of medicine and agriculture. It can be used to synthesize indole derivatives, such as indole carboxylate derivatives, which have antitumor and antiviral activities in the pharmaceutical field. In addition, 1H-Indole, 7-bromo-3-iodo-can also be used as pesticide intermediates for the synthesis of compounds having insecticidal activity.
Preparation Method:
The method of preparing 1H-Indole, 7-bromo-3-iodo-is generally obtained by taking indole as a starting material and transforming it through a series of chemical reactions. A common synthetic method is to brominate indole with bromine chloride and then react the resulting product with hydroiodic acid to give 1H-Indole, 7-bromo-3-iodo-.
Safety Information:
Due to the toxicity and irritation of 1H-Indole, 7-bromo-3-iodo-during preparation and use, corresponding safety measures should be taken. Personal protective equipment such as protective gloves, goggles and protective clothing are required to be worn during operation to avoid contact with skin and inhalation. At the same time, it also needs to be stored in a dry and ventilated place, away from fire and oxidant, and has potential harm to the environment, and requires proper treatment and relevant regulatory measures for waste disposal. In the process of use and handling, it is necessary to comply with the relevant regulations for the transportation, storage and handling of dangerous goods.
Last Update：2024-04-09 21:11:58
